Logo of TANGO2 Research Foundation featuring colorfully stylized vertical shapes next to the text 'TANGO2 Research Foundation'.

The TANGO2 Research Foundation: Grassroots to Global Impact

Leading the charge in rare disease research and patient advocacy.

The TANGO2 Research Foundation was born out of a fifteen-year diagnostic odyssey that finally ended in 2017—not with answers, but with a name for a disease science barely understood. For Mike and Kasha Morris, the long-awaited diagnosis brought a poor prognosis and a terrifying realization: a clock was ticking for their son, Ryan, and they had no way of knowing how fast. With almost no information available and Ryan’s life hanging in the balance, their singular focus was to bring immediate attention to this newly discovered genetic condition.

What began as a desperate race to save one child has since transformed into a global movement. Driven by the belief that no family should face this uncertainty alone, the foundation now coordinates world-class research and provides a lifeline of hope to families in more than 30 countries. From a kitchen table in Connecticut to an international scientific powerhouse, the mission remains the same. By funding and guiding global research, the foundation is rapidly accelerating the path to treatments and a brighter future for every child living with TANGO2.

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The Discovery

It began with a parent's hunch and a simple multivitamin. We bridge the gap between "unexplained symptoms" and life-saving treatments, proving that the answers are often hidden in plain sight.

Three smiling individuals, two adults and one young person, wearing dark blue conference T-shirts with 'Houston 2019' printed on them, sitting close together with arms around each other in an indoor setting.

The Foundation

Co-founded by Kasha and Mike Morris, the Foundation has grown into an international force for medical progress. As members of the CZI Rare As One Network, we are accelerating TANGO2 research at an unprecedented pace.

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The Future

Our mission isn't over until every family has a cure. We are building a global community united by hope, grit, and the unwavering belief that the impossible is just a milestone.